Michael Jackson's Moonwalker (MegaDrive / Genesis)

Revolution X (SNES)
Aerosmith joined the suprisingly long list of bands with videogames to their names with Revolution X, a sub-par lightgun game centered around the band's fight against an evil dictatorship. Hey, at least it isn't an Insane Clown Posse game.
Of course, Revolution X featured synthesised versions of many Aerosmith tracks, the best of the bunch probably being "Rag Doll" as featured in the SNES version's intro:
Highlander (C64)
Wayne's World (SNES)

Wanted: Monty Mole (C64)

This one's pure, unrefined nostalgia for me: I think Monty Mole was the first videogame I ever owned. That the theme song allowed me to sing along with a song about Hitler's alleged monorchism was an added bonus.
Mikie (Arcade)

Parodius (Various)

This is a personal favourite: "Hot Lips" from Sexy Parodius, a demented version of Jaques Offenbach's "The Galop from Orpheus in the Underworld". That's the can-can music to you and me, and never would I have believed it could have been such a perfect fit with a videogame about shooting things.
Rock n' Roll Racing (SNES)
Simply wonderful.
Doom (PC)

Ghostbusters (C64)

As I recall, if you pressed a button at the appropriate time during the song, some digitised speech would warble "Ghostbusters!" at you. That, my friend, is the reason mankind was put on this earth.
Tetris (Game Boy)

Very Russian indeed, and appropriately so. It was originally written in 1861, and when I finally get my time machine working the first thing I'm gonna do is grab a Game Boy, travel back to ninteenth-century Russia and show the guy who wrote this how his creation is going to be remembered for many, many years. I hope he's pleased.
And that's it for this installment. There are many, many more instances of real songs being used in retro videogames, so maybe there'll be a part two to this article. As for the mean time, I promise I won't tell anyone you were singing along to the Ghostbusters theme.